인공타액에서 은-함유 결찰용 고무링의 은 이온 유리량에 대한 평가
Evaluation of Silver Ion Release from Silver-containing Elastomers in Artificial Saliva
안진수, 황은주, 이동렬, 임용규,
소속 상세정보
안진수 ( Ahn Jin-Soo ) - 서울대학교 치의학대학원 치과생체재료과학교실
황은주 ( Hwang Eun-Ju ) - 고려대학교 임상치의학대학원 치과교정학과
이동렬 ( Lee Dong-Yul ) - 고려대학교 임상치의학대학원 치과교정학과
임용규 ( Lim Yong-Kyu ) - 고려대학교 임상치의학대학원 치과교정학과
KMID : 0362220100370040297
Abstract
The aim of this in-vitro investigation was to determine the amount and pattern of silver ion release from silver-
containing elastomers in artificial saliva. Open group (n=10, the cap of each bottle was opened on a regular
basis during the experiment) and Seal groups (n=40, the cap of the bottle was remained closed throughout the
experiment) consisted of polystyrene bottles containing 2mL of artificial saliva maintained at 37℃ in oven with 20
silver-containing elastomers stretched over stainless steel brackets placed in each individual bottles. A polystyrene
bottle containing only artificial saliva and 20 stainless steel brackets was used as control. The amount of
silver ion release was measured once a day for 7 days (T1 - T7) and then once a week (T8 - T10) for the following
3 weeks in Open group. After the supernatant solution was decanted to measure the amount of ion release,
fresh artificial saliva was added in each bottle. In Seal groups (S - 1, 2, 3, 4), cumulative silver ion was measured
after 1, 2, 3 and 4 weeks for each group without changing sample solutions. Control was also measured after
4 weeks. Following results were obtained. The silver-containing elastomer showed a high initial silver ion release
during the first week and showed declining tendency in the amount of silver ion release over the time period in
both Open and Seal groups. Open group showed higher amount of daily ion release than Seal groups which may
be attributed to the oxygen contact in Open group. Thus, the initial burst of silver ion release and the varying
conditions of oral environment should be taken into consideration in the clinical use of silver-containing elastomer.
키워드
Antibacterial; Artificial saliva; Elastomer; Release; Silver ion
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